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Fungal infections

Fungi are everywhere – on and in our bodies and in the air we breathe, the food we eat and the water we drink. Fortunately, most of them are harmless; and some are even essential. Indeed, fungi are used to make bread, cheese, beer and wine, and truffles and mushrooms are also types of fungi.

Occasionally, however, this peaceful coexistence goes wrong and a harmless fungal inhabitant becomes troublesome. We distinguish between fungal infections of the body surfaces and systemic fungal infections (which affect the whole body or an organ).

Fungal infections of body surfaces
Fungal infections of the skin are the commonest type of fungal infection. They are contracted through direct or indirect contact with other infected people, animals or soil. As they are often unsightly and uncomfortable conditions they can have both physical and psychological consequences. Well-known fungal diseases include athlete's foot, pityriasis versicolor, fungal infection of the vagina (candidosis) and fungal nail disease (onychomycosis). Fungi also play a role in dandruff.

Onychomycosis, for instance, affects 1 to 3% of the population, and is characterised by discoloration and thickening of the nail and detachment of the nail plate from the nail bed. Toenails, which are frequently the primary site of infection, are often thick, yellow and brittle, and debris accumulates under the nail.

Systemic fungal infections

Although systemic fungal infections are relatively rare, their incidence has risen during the past 20 years. This is because of increases in the number of people with diminished or impaired immunity. Immune defences are reduced during certain hospital treatments, such as chemotherapy for cancer, and in some diseases, such as HIV infection. Fungal infections

In such persons, fungi behave as opportunist invaders and can cause life-threatening infections. Many systemic infections arise from fungi that enter the body via the lungs; others involve fungi that enter the body by routes such as the digestive tract.

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