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| Cutting edge technologies |
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| A New Paradigm |
| We are creating a new paradigm for quality,
quantity and speed by taking advantage of
emerging technologies. |
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Reducing the drug discovery
and development cycle time will
provide safe, effective, cost-effective
drugs more quickly.
We are significantly shortening
time from assay screening to
recommendation of a new chemical
entity for development. Drug
discovery and development scientists
work together to speed recommendation
of candidates for development.
They partner with clinicians
to begin clinical testing as
soon as it is safe to do so.
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| With the
use of Combinatorial Chemistry and Parallel
Synthesis technology our chemists are
individually producing up to fifty compounds
a month. As new automated assay
and chemical synthesis technologies
develop, our goal is to triple the number
of NCEs brought into development and
to screen 10,000 distinct compounds
a week per assay. To achieve this goal
we are utilising large, diverse compound
libraries and new technologies that
have changed the nature of drug discovery:
Combinatorial
Chemistry, High
Throughput Screening, Molecular
Modeling, Bioinformatics,
Human
Receptor Culture, Human
Genome Mapping, Positional
Gene Cloning. |
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Evolving
Information Culture
The overwhelming volume of information
that is produced by these new technologies
requires sophisticated management methods.
All information gathered about a compound
including data from primary screens,
secondary assays, about the chemistry
and pharmacology are collected into
a fully integrated database accessible
to scientists. Our robust computing
network allows scientists in various
locations to work as a team. |
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